Menü Überspringen
Contact
Deutsch
English
Not track
Data Protection
Search
Log in
DIPF News
Research
Infrastructures
Institute
Zurück
Contact
Deutsch
English
Not track
Data Protection
Search
Home
>
Research
>
Publications
>
Publications Data Base
Search results in the DIPF database of publications
Your query:
(Schlagwörter: "Verhaltensgenetik")
Advanced Search
Search term
Only Open Access
Search
Unselect matches
Select all matches
Export
Highs and lows. Genetic susceptibility to daily events
Sicorello, Maurizio; Dieckmann, Linda; Moser, Dirk; Lux, Vanessa; Luhmann, Maike; […]
Journal Article
| In: PLoS ONE | 2020
40505 Endnote
Author(s):
Sicorello, Maurizio; Dieckmann, Linda; Moser, Dirk; Lux, Vanessa; Luhmann, Maike; Neubauer, Andreas B.; Schlotz, Wolff; Kumsta, Robert
Title:
Highs and lows. Genetic susceptibility to daily events
In:
PLoS ONE, (2020) 15, S. e0237001
DOI:
10.1371/journal.pone.0237001
URN:
urn:nbn:de:0111-dipfdocs-232683
URL:
https://nbn-resolving.org/urn:nbn:de:0111-dipfdocs-232683
Publication Type:
3a. Beiträge in begutachteten Zeitschriften; Aufsatz (keine besondere Kategorie)
Language:
Englisch
Keywords:
Person; Gen; Serotonin; Einflussfaktor; Umgebung; Ereignis; Emotionaler Zustand; Belastung; Verhaltensgenetik; Smartphone; Online; Befragung; Bochum; Deutschland
Abstract (english):
Why people differ in their susceptibility to external events is essential to our understanding of personality, human development, and mental disorders. Genes explain a substantial portion of these differences. Specifically, genes influencing the serotonin system are hypothesized to be differential susceptibility factors, determining a person's reactivity to both positive and negative environments. We tested whether genetic variation in the serotonin transporter (5-HTTLPR) is a differential susceptibility factor for daily events. Participants (N = 326, 77% female, mean age = 25, range = 17-36) completed smartphone questionnaires four times a day over four to five days, measuring stressors, uplifts, positive and negative affect. Affect was predicted from environment valence in the previous hour on a within-person level using three-level autoregressive linear mixed models. The 5-HTTLPR fulfilled all criteria of a differential susceptibility factor: Positive affect in carriers of the short allele (S) was less reactive to both uplifts and stressors, compared to homozygous carriers of the long allele (L/L). This pattern might reflect relative affective inflexibility in S-allele carriers. Our study provides insight into the serotonin system's general role in susceptibility and highlights the need to assess the whole spectrum of naturalistic experiences.
DIPF-Departments:
Bildung und Entwicklung
Unselect matches
Select all matches
Export